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Many countries in all over the world generate
2019-11-16
Many countries in all over the world generate a large amount of RHA from uncontrolled and controlled burning. RHA is a pozzolanic material due to this high percentage of SiO2 in RHA. Rice husk ash, as a mineral additive, is produced by burning rice husks, which are obtained in the rice milling indus
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IY-5511 br Results br Discussion Mucosal barriers are
2019-11-16
Results Discussion Mucosal barriers are constitutively challenged by various stimuli, and the homeostasis of mucosal barriers both at steady state and upon challenge are maintained by tissue-resident immune IY-5511 (Kurashima et al., 2013, Okumura and Takeda, 2016). ILC3s are found in lymphoi
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PI K Akt eNOS signaling is long been
2019-11-15
PI3K-Akt-eNOS signaling is long been known as a cell survival pathway in cardiology [8]. Current study has shown that ginsenosides, which is demonstrated to exhibit cardioprotective effect in several aspects, prevented cardiac ischemia/reperfusion injury via upregulation of PI3K and phosphorylations
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lobeline mg Tailoring pharmacological treatment to the genet
2019-11-15
Tailoring pharmacological treatment to the genetic background of a person can enhance therapeutic response (), increase compliance (), and decrease drug toxicity (, , ). Because cocaine addiction has a strong genetic basis, with the vulnerability to develop an addiction estimated to be as high as 72
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DNA damage represents a persistent
2019-11-15
DNA damage represents a persistent threat to genomic stability. A critical link exists between DNA mutation, chromosomal rearrangement and cancer development. In myeloid malignancies, various chromosomal translocations and/or mutations increased cellular reactive oxygen species (ROS), followed by DS
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Previous studies from our lab looked at the effect of
2019-11-15
Previous studies from our lab looked at the effect of interfering with crossover helix interactions in TS-DHFR. One study utilized peptide mimetics of the crossover helix to inhibit wild-type TS-DHFR noncompetitively, and with an IC of 230 μM. A second study used a virtual screening approach to iden
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br Introduction To detect exposure
2019-11-15
Introduction To detect exposure to and effects of neuroactive pesticides in aquatic organisms, one widely used biomarker is cholinesterase (ChE) activity, which, among other possible functions, catalyzes the hydrolysis of the neurotransmitter 5 03 (ACh) in the cholinergic synapses of the central
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Therefore the relationship between ChEs activity
2019-11-15
Therefore, the relationship between ChEs activity and polymorphisms in POT1, TERF1, TERT genes were explored in order to screen susceptible biomarkers in this study. Materials and methods Results Discussion However, genetic toxicity induced by OPs has not been fully investigated so far. Ca
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br Conflict of interest br Acknowledgements This study
2019-11-15
Conflict of interest Acknowledgements This study was supported by the National Natural Science Foundation of China (No.31571839), the Chinese Ministry Program for New Century Excellent Talents in University (NCET-12-0865), and Special Fund for Agro-scientific Research in the Public Interest (N
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Here we were able to show for
2019-11-15
Here, we were able to show for the first time that stimulation of VSMCs with two different growth factors resulted in a dramatic decrease in gp130mRNA expression occurring four to six hours after stimulation with Ang II and PDGF-BB. The mRNA level remained extremely low within 12 hours after stimula
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In conclusion the results obtained in this study
2019-11-15
In conclusion, the results obtained in this study and those recently reported by our group (Abdel-Samad et al., 2012) clearly indicate that a dialogue indeed exists between the systems of NPY and ET-1 at the level of human endocardial endothelial cells, since these cells, whether isolated from the r
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Moving forward the new mathematical
2019-11-14
Moving forward, the new mathematical model opens doors for understanding the SCF network, where activity of a component is blunted through mutation or altered in expression in diseased states, and during therapeutic intervention. Computational modeling could reveal underappreciated secondary or tert
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Because of the important role of the DDB
2019-11-14
Because of the important role of the DDB1-CUL4B interaction for CUL4B-based E3 ligases, disruption of the DDB1-CUL4B interaction could be an effective approach to treat cancer. Therefore, we developed an in vitro HTS assay based on yeast cell growth inhibition to identify compounds that could disrup
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Concholepas concholepas our model species
2019-11-14
Concholepas concholepas, our model species for this study, is a marine gastropod found along the Chilean coast that has become commercially important [25], [26], [27]. Until now, the main focus of immunology related to C. concholepas is the production of a novel hemocyanin that has been useful for t
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Recent results from our group found that SPMs
2019-11-14
Recent results from our group found that SPMs, not only play a part in terminating inflammation, but also have a physiological role in conjunctival goblet 84 to maintain ocular surface health in the absence of disease. Amongst the SPMs that are effective in the conjunctiva are resolvin D1 (RvD1), a
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