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In the NGS era many rare variants
2019-04-29
In the NGS era, many rare variants can be detected in genetic analysis, some of which are related with the disease. Therefore, the true mutation(s) causative for the disease need to be distinguished from other genetic noise. In 2011, Kapplinger et al. reported background genetic noise in ARVC [49].
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br Conclusion br Funding br Conflict of interest
2019-04-29
Conclusion Funding Conflict of interest Introduction Over the last decade, the unabated increase in the number of transseptal catheterizations has been related to an increase in atrial fibrillation (AF) ablation procedures. Transseptal puncture (TP) is usually safe in experienced hands [
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Ahora bien el inter s de Vigil por la
2019-04-29
Ahora bien, el interés de Vigil por la historia nacional está fuertemente vinculado con sus labores magisteriales y su trabajo como director de la Biblioteca Nacional. Estas labores orientaron sus reflexiones sobre la historia hacia un enfoque pedagógico, en donde se destaca la importancia del estud
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Introduction Leukaemias lymphomas and multiple myeloma can b
2019-04-29
Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf
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En numerosas ocasiones Ricardo Piglia ha creado una met
2019-04-28
En numerosas ocasiones, Ricardo Piglia ha creado una metáfora de su poética con la figura de un signo lingüístico dual que enlaza lo estético con lo social. Su obra se ha colocado dentro de la gran tradición literaria argentina de manera explícita, Ramelteon partir de las polémicas desatadas por sus
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br In WHO announced a plan
2019-04-28
In 2015, WHO announced a plan to end tuberculosis by 2035 (their End TB Strategy) and set ambitious intermediate targets to reduce tuberculosis incidence by 50% and mortality by 75% by 2025. In , two related papers by Rein Houben and Nicolas Menzies and their colleagues describe the results of a u
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HBeAg positive patients older than years with persistently h
2019-04-28
HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o
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br Introduction Percutaneous transcatheter device closure of
2019-04-28
Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective
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Al frente de esa disputa Jorge
2019-04-28
Al frente de esa disputa, Jorge Cuesta mostró que la verdadera tradición mexicana no era nacionalista sino cosmopolita, universal; sin duda, estos poemas de Hora y 20, por lo menos, ayudan ache inhibitor comprender la avidez por romper los límites que prevalecía en la mentalidad poética de los Conte
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Baseline lead ECGs from immediately prior to S
2019-04-28
Baseline 12-lead ECGs from immediately prior to S-ICD implantation were reviewed for all patients. Baseline intervals (PR, QRS, QT) were obtained from the automated ECG measurements. Leads I, II, and aVF were further used to collect data on QRS and T wave amplitudes, QRS/T amplitude ratio, presence
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br Conflict of interest br Case presentation A
2019-04-28
Conflict of interest Case presentation A 41-year-old man with a history of palpitations refractory to multiple antiarrhythmic agents for several weeks was referred to our department. A 12-lead electrocardiogram (ECG) demonstrated incessant narrow QRS complex tachycardia (cycle length of 580ms)
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The data obtained in our work
2019-04-28
The data obtained in our work showed that AMD was able to inhibit complex I activity and ATP biosynthesis in MRC-5 cells. These effects were accompanied by an increase in lipid and protein oxidative damage and a decrease in NO levels and superoxide dismutase and catalase activities, suggesting that
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br Conclusions and future perspectives br Conflict of
2019-04-28
Conclusions and future perspectives Conflict of interest Author’s contributions Introduction Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two opposing mechanisms involved in regulating the chemical and functional homeostasis of end
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En raz n del desarrollo que
2019-04-28
En razón del desarrollo que la oposición entre el individuo y la colectividad ha cobrado en Occidente, y cada vez es más aguda, se han entendido o malentendido las demandas de los pueblos indígenas como contrarias heme oxygenase los derechos individuales, pero tal perspectiva es reduccionista, ya qu
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br CUANDO EL CUERPO SE HACE ESPACIO
2019-04-28
CUANDO EL CUERPO SE HACE ESPACIO El punto en común de estos lienzos es la ausencia de mirada (figuras 3a y 3b). En el primero los ojos están negros, se presentan las dos órbitas vacías; en el segundo están deliberadamente borrados, ya que incluso se puede distinguir por debajo el contorno de los
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